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FastTrack PGx Results: empowering timely tailored prescriptions and precision medicine

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This innovation envisions a near-future where every Veteran could benefit from Pharmacogenomics (PGx). PGx drives tailoring medications based on an individual's genetic profile. PGx can be leveraged to optimize drug effectiveness while limiting side effects. By utilizing PGx, clinicians can eliminate the trial-and-error and guesswork in prescribing: the RIGHT drug at the RIGHT dose for the RIGHT patient.

To set the stage in ensuring PGx thrives at the VA, we are developing agile solutions for the timely return of PGx results, making them readily accessible to the prescribing clinician. We are committed to
addressing the lack of interoperability and integration between the VA's electronic health records (CPRS) and the laboratory that provides the PGx results. This ambitious innovation boldly kicks it up a notch: the RIGHT drug at the RIGHT dose for the RIGHT patient at the RIGHT time (i.e. at the critical point-of-prescribing).

This innovation is replicating across multiple facilities as its impact continues to be validated. See more replicating innovations.

Adoptions:

3 successful

Awards and Recognition:

(1) Senior Innovation Fellow, FY2024, (2) Director's Pick, Shark Tank Finalist, FY2025, (3) Selected project abstract for 2024 AMSUS Association of Military Surgeons of the United ... (1) Senior Innovation Fellow, FY2024, (2) Director's Pick, Shark Tank Finalist, FY2025, (3) Selected project abstract for 2024 AMSUS Association of Military Surgeons of the United States- The Society of Federal Health Professionals, National Harbor, MD, (4) Selected project abstract for 2024 Tri-Con Precision Medicine Conference, San Diego, CA, (5) Selected project abstract for 2024 AGBT Advances in Genome Biology and Technology, Aurora, CO, (6) Selected project abstract for 2024 Stanford Lean Academic Conference, Palo Alto, CA, (7) Selected project abstract for 2024 ASHG American Society of Human Genetics, Denver, CO, (8) This project was a featured article published by high-impact international Precision Medicine Journal, GenomeWeb, August 19, 2024 (VA Aims to Automate Input of Pharmacogenomic Data Into EHR, Studying Impact of Recommendations), (9) Impact of PGx in Mental Health, invited speaker for Sutter Healthcare Virtual Forum, July 2024, Sacramento, CA (sutterhealth.org), (10) The Healthcare Innovation Congress 2024, invited panelist for Federal Healthcare Innovations, Washington DC (www.thinc360.com) , (11) 2024 FORUM IMPACT Women in Leadership Award for this fellowship work (https://events.govforum.io/leading-for-impact-women-in-leadership/#winners)

Partners:

Innovation Ecosystem

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Metrics

  • #Veterans who agree to PGx testing = #Veterans who can benefit from timely return of PGx results. Tracking this metric monthly.
  • #Prescribing clinicians who stay engaged (proxy measure: #PGx tests ordered). Clinicians will not order PGx tests if obtaining the PGx results is time-consuming and burdensome. Tracking this metric monthly.
  • Prescriber's satisfaction survey.
  • Veteran's (patient's) satisfaction survey.
  • Cost analyses: amount of human labor costs (manual data entry).
  • Time loss calculations: Time wasted on human-made errors or miscommunications.
  • Operational bottlenecks: inability to connect to resource where PGx results are stored,
  • Using CD-10-CM codes, track drug adverse effects or drug intolerance and investigate concordance with PGx results

Diffusion tracker

Does not include Clinical Resource Hubs (CRH)

Statuses

There are no in-progress adoptions for this innovation.

There are no unsuccessful adoptions for this innovation.

Multimedia

Videos

Above:

Pharmacogenomics: When One Size Does NOT Fit All